This assumes fresh installation of your Linux, also change the terminal commands to your distro of choice.
The command I included was for my Arch-based distro, check the link if there are commands for your distro.
1. Follows https://github.com/lutris/docs/blob/mas ... dencies.md and install Wine-staging with all dependencies
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sudo pacman -S --needed wine-staging giflib lib32-giflib libpng lib32-libpng libldap lib32-libldap gnutls lib32-gnutls mpg123 lib32-mpg123 openal lib32-openal v4l-utils lib32-v4l-utils libpulse lib32-libpulse libgpg-error lib32-libgpg-error alsa-plugins lib32-alsa-plugins alsa-lib lib32-alsa-lib libjpeg-turbo lib32-libjpeg-turbo sqlite lib32-sqlite libxcomposite lib32-libxcomposite libxinerama lib32-libgcrypt libgcrypt lib32-libxinerama ncurses lib32-ncurses opencl-icd-loader lib32-opencl-icd-loader libxslt lib32-libxslt libva lib32-libva gtk3 lib32-gtk3 gst-plugins-base-libs lib32-gst-plugins-base-libs vulkan-icd-loader lib32-vulkan-icd-loader
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sudo pacman -S lutris
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yay -S dxvk-bin
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sudo pacman -S --needed nvidia-settings nvidia lib32-nvidia-utils nvidia-utils
5. Reboot your computer.
6. Make sure you use lutris's wine binaries and not the wine-staging that was installed separately in step 1.
7. Enjoy!